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Review of Ebola response provides context for future infection control recommendations

National recommendations and strategies are needed to help hospitals prepare for potential Ebola cases and other emerging infectious diseases.

Towards a pan-ebolavirus treatment

In 2014, the alarm for the Zaire Ebola virus was sounded around the world - but there are other deadly ebolaviruses that cause identical symptoms, and they have even fewer treatment options.

Ebola vaccine: Promising phase I trials

"The results for tolerability, safety, and the immune response to the vaccine candidate are very promising," explains Prof Marylyn Addo.

Cancer drug may treat sepsis, other uncontrollable immune responses to infection

NIH-funded study reveals topoisomerase 1 inhibitors suppress inflammation in mice.

Ebola virus genome provides clues to repeated disease 'flare-ups' in Western Africa

Ebola virus samples taken from patients in Liberia in June 2015 are strikingly similar in their genetic makeup to other Ebola virus sequences from Western Africa, according to research published...

Cellphone-sized device quickly detects the Ebola virus

The worst of the recent Ebola epidemic is over, but the threat of future outbreaks lingers.

Infectious outbreaks must be combatted strategically, Dartmouth-HHS experts argue

New funding is not enough to guarantee success against emerging infectious diseases around the world.

Clinical trial for experimental Ebola drug publishes results

Rapid assessment approach finds TKM-130803 ineffective at the dose given. Results of the Wellcome Trust funded trial of the experimental anti-Ebola drug TKM-130803 have been published April 19 in...

Study examines safety, immune response of candidate Ebola vaccines

In a study appearing in JAMA, Matthew D. Snape, F.R.C.P.C.H., M.D., of the University of Oxford, United Kingdom, and colleagues conducted a phase 1 trial to evaluate the tolerability and...

Uninfected or asymptomatic? Diagnostic tests key to forecasting major epidemics

Major epidemics such as the recent Ebola outbreak or the emerging Zika epidemic may be difficult to forecast because of our inability to determine whether individuals are uninfected or infected but...

NIH doctors describe severe case of Ebola virus disease

For more than a month in 2015, a multidisciplinary team including infectious disease and critical care physicians and nurses, respiratory therapists and other specialists at the National Institutes...

UN's interventions in Sierra Leone significantly slowed Ebola

The United Nations' interventions in the Sierra Leone Ebola outbreak led to a dramatic drop in the transmission of the disease, according to a study led by a University of Florida Health researcher.

Ebola in West Africa 'no longer global emergency,' WHO report

Following an expert panel's advice, WHO declare the Ebola situation in West Africa is no longer a global health threat, although small clusters of new cases are still expected.

Automated Ebola blood test performs well in field evaluation

An automated "sample-to-answer" system could provide Ebola virus disease (EVD) diagnosis more quickly and easily than the current standard test, according to research published in PLOS Medicine.

Stanford scientists resurrect an abandoned drug, find it effective against human viruses

Viruses have proven to be wily foes. Attempts to fend off viruses causing even the common cold or flu have failed, and new viral outbreaks such as dengue, Ebola or Zika continue to elude drugs.

Sweet 'quantum dots' light the way for new HIV and Ebola treatment

A research team led by the University of Leeds has observed for the first time how HIV and Ebola viruses attach to cells to spread infection.

New nanoparticle technology to decipher structure and function of membrane proteins

Researchers at Karolinska Institutet, Sweden, have developed a nanoparticle technology that can be used to stabilise membrane proteins so that their structure can be studied in a lipid environment.

Nuanced findings for a large experimental treatment trial for Ebola virus disease

While not conclusive, valuable research generated through researching an experimental treatment for Ebola virus disease in Guinea during the recent Ebola outbreak will support future research into...

Risk of catching Ebola from survivor 'very low' if there is no sexual intercourse

New research from the University of East Anglia shows that the risk of catching Ebola from a survivor is very low.